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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLCL1 All Species: 22.12
Human Site: S944 Identified Species: 37.44
UniProt: Q15111 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15111 NP_006217.3 1095 122728 S944 S D N T P S V S L V M K D S F
Chimpanzee Pan troglodytes XP_001169560 1095 122728 S944 S D N T P S V S L V M K D S F
Rhesus Macaque Macaca mulatta XP_001089483 1095 122754 S944 S D N T P S V S L V M K D S F
Dog Lupus familis XP_536020 1096 122535 S945 S D N T P T V S L V M K D N F
Cat Felis silvestris
Mouse Mus musculus Q3USB7 1096 122654 S945 S D S T P S V S L V M K D C F
Rat Rattus norvegicus Q62688 1096 122754 S945 S D S T P S V S L V M K D C F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507313 1051 118878 V901 P D N T S L V V L N L S D Q F
Chicken Gallus gallus Q2VRL0 637 72514 P524 L I S G H Q L P P S N L S K S
Frog Xenopus laevis Q32NH8 758 87399 I645 E N S K E G S I V D P L V R V
Zebra Danio Brachydanio rerio A5D6R3 784 89362 V671 I V D P Q V W V E I H G V S I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13217 1095 124845 N935 R N D A N I K N S I N D Q T K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_741067 1068 120024 P903 L A V N S S P P P S P T T S S
Sea Urchin Strong. purpuratus XP_001178766 684 77475 A571 R S L F N R L A K T T E P V S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32383 869 100529 N756 N D T S P S R N N T N S F V K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 98.7 96.4 N.A. 94.3 94.1 N.A. 62.9 21.7 24.7 27.9 N.A. 20 N.A. 39 35.8
Protein Similarity: 100 100 99.2 98.5 N.A. 96.6 96.6 N.A. 77.1 34.8 40.4 42.3 N.A. 40.2 N.A. 59.4 48.1
P-Site Identity: 100 100 100 86.6 N.A. 86.6 86.6 N.A. 46.6 0 0 6.6 N.A. 0 N.A. 13.3 0
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 53.3 13.3 20 20 N.A. 33.3 N.A. 13.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 37.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 8 0 0 0 8 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 15 0 % C
% Asp: 0 58 15 0 0 0 0 0 0 8 0 8 50 0 0 % D
% Glu: 8 0 0 0 8 0 0 0 8 0 0 8 0 0 0 % E
% Phe: 0 0 0 8 0 0 0 0 0 0 0 0 8 0 50 % F
% Gly: 0 0 0 8 0 8 0 0 0 0 0 8 0 0 0 % G
% His: 0 0 0 0 8 0 0 0 0 0 8 0 0 0 0 % H
% Ile: 8 8 0 0 0 8 0 8 0 15 0 0 0 0 8 % I
% Lys: 0 0 0 8 0 0 8 0 8 0 0 43 0 8 15 % K
% Leu: 15 0 8 0 0 8 15 0 50 0 8 15 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 43 0 0 0 0 % M
% Asn: 8 15 36 8 15 0 0 15 8 8 22 0 0 8 0 % N
% Pro: 8 0 0 8 50 0 8 15 15 0 15 0 8 0 0 % P
% Gln: 0 0 0 0 8 8 0 0 0 0 0 0 8 8 0 % Q
% Arg: 15 0 0 0 0 8 8 0 0 0 0 0 0 8 0 % R
% Ser: 43 8 29 8 15 50 8 43 8 15 0 15 8 36 22 % S
% Thr: 0 0 8 50 0 8 0 0 0 15 8 8 8 8 0 % T
% Val: 0 8 8 0 0 8 50 15 8 43 0 0 15 15 8 % V
% Trp: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _